MersV1, Main, Exploration, bibRecord, 001490

A new role of neuraminidase (NA) in the influenza virus life cycle: implication for developing NA inhibitors with novel mechanism of action

Identifieur interne : 001490 ( Main/Exploration ); précédent : 001489; suivant : 001491

A new role of neuraminidase (NA) in the influenza virus life cycle: implication for developing NA inhibitors with novel mechanism of action

Auteurs : Jie Yang [République populaire de Chine, États-Unis] ; Shuwen Liu [République populaire de Chine] ; Lanying Du [États-Unis] ; Shibo Jiang [République populaire de Chine, États-Unis]

Source :

Reviews in Medical Virology [ 1052-9276 ] ; 2016-07.

RBID : ISTEX:1CDF8FA1D975164E900CDC3C7F5CB75E649A3A48

Abstract

The entire life cycle of influenza virus involves viral attachment, entry, replication, and release. Previous studies have demonstrated that neuraminidase (NA) is an essential glycoprotein on the surface of influenza virus and that it is responsible for release of progeny virions from the host cell to infect new cells. However, recent studies have also suggested that NA may play other roles in the early stages of the viral life cycle, that is, viral attachment and entry. This review focuses on the new role of NA in the early stages of influenza life cycle and the corresponding development of novel NA inhibitors. Copyright © 2016 John Wiley & Sons, Ltd.

Url:

https://api.istex.fr/ark:/67375/WNG-CKSXGZ23-P/fulltext.pdf

DOI: 10.1002/rmv.1879

Affiliations:

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Le document en format XML

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<front><div type="abstract">The entire life cycle of influenza virus involves viral attachment, entry, replication, and release. Previous studies have demonstrated that neuraminidase (NA) is an essential glycoprotein on the surface of influenza virus and that it is responsible for release of progeny virions from the host cell to infect new cells. However, recent studies have also suggested that NA may play other roles in the early stages of the viral life cycle, that is, viral attachment and entry. This review focuses on the new role of NA in the early stages of influenza life cycle and the corresponding development of novel NA inhibitors. Copyright © 2016 John Wiley & Sons, Ltd.</div>
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A new role of neuraminidase (NA) in the influenza virus life cycle: implication for developing NA inhibitors with novel mechanism of action

A new role of neuraminidase (NA) in the influenza virus life cycle: implication for developing NA inhibitors with novel mechanism of action

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Abstract

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Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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